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缺氧诱导的肺高血压后的血管内血栓形成:通过循环氧基酶-2调节

Graham P Pidgeon1, Rasa Tamosiuniene, Gang Chen

  • 1Department of Clinical Pharmacology, Royal College of Surgeons Ireland, 123 St. Stephens Green, Dublin 2, Ireland. gpidgeon@rcsi.ie

Circulation
|October 20, 2004
PubMed
概括

循环氧化原酶-2 (COX-2) 抑制通过增加血栓素A2和血小板激活,使缺氧诱导的肺高血压恶化. 在这种情况下,COX-2在调节血管反应和血栓形成方面发挥着关键作用.

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