糖因素:树突性酸糖体表现的胰岛素,显示出长时间的降血糖活性

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Identification and Characterization of Protein Glycosylation using Specific Endo- and Exoglycosidases
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Identification and Characterization of Protein Glycosylation using Specific Endo- and Exoglycosidases

Published on: December 26, 2011

Masaaki Sato1, Tetsuya Furuike, Reiko Sadamoto

  • 1Division of Biological Sciences, Graduate School of Science, Frontier Research Center for Post-Genomic Science and Technology, Hokkaido University, Kita 21 Nishi 11, Sapporo 001-0021, Japan.

Journal of the American Chemical Society
|October 28, 2004
PubMed
概括

使用alpha2,6-sialyltransferase (alpha2,6-SiaT) 和转谷氨酸酶 (TGase) 延长胰岛素的酸修饰在高血糖小鼠中降低葡萄糖的作用. 三氧化甘氨酸显示出葡萄糖水平恢复的显著延迟.

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