在患者慢性心房的心上映图:初步观察
Jayakumar Sahadevan1, Kyungmoo Ryu, Leora Peltz
1Department of Medicine, Division of Cardiology, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, The Louis B. Stokes Veterans' Administration Medical Center, Cleveland, Ohio 44106, USA.
Circulation
|November 3, 2004
概括
慢性心房动 (AF) 的机制尚不清楚. 在9名患者中,心图显示出快速,规律的心房节律的常见模式,这表明导致动导电的驱动器是关键的AF机制.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏外科手术 心脏外科手术
背景情况:
- 慢性心房动 (AF) 的潜在机制尚未完全理解.
- 调查AF需要在相关患者群体中使用先进的测绘技术.
研究的目的:
- 为了测试慢性AF是由局部,快速的心房节律驱动的假设.
- 确定慢性AF中心房激活模式的来源和特征.
主要方法:
- 使用404个电极对9名因慢性AF接受心脏开放手术的患者进行心上图谱绘制.
- 对心房电图 (AEG) 和快速里埃转换 (FFT) 进行激活模式的分析.
- 在心肺绕道术期间和之前进行记录,以捕捉AF动态.
主要成果:
- 在慢性AF患者中观察到两种不同的心房激活模式.
- 模式1 (7/9患者) 显示了短,规律的周期长度,在特定的心房区域具有一致的形态,暗示着一个驱动器.
- 这种驱动因素最常发生在左心室 (5/7),有时发生在右心室或两者之间.
结论:
- 在慢性AF患者中最常见的AEG模式表明局部区域的快速,规律的节奏.
- 这一发现支持这样一个假设:"驱动器"导致纤维导电是慢性AF的重要机制.
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