臭氧和95个美国城市社区的短期死亡率,1987-2000年
Michelle L Bell1, Aidan McDermott, Scott L Zeger
1School of Forestry and Environmental Studies, Yale University, New Haven, Conn 06511, USA. michelle.bell@yale.edu
JAMA
|November 18, 2004
概括
在95个美国城市社区中,短期暴露于环境臭氧显著增加了日常死亡率,包括心血管和呼吸道死亡. 这项研究证实了臭氧是广泛存在的污染物,对公众健康产生不利影响.
科学领域:
- 环境健康科学 环境健康科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 臭氧暴露与不良健康结果有关,包括呼吸道问题和住院治疗.
- 之前关于臭氧和死亡率的时间序列研究得出了不确定的结果.
研究的目的:
- 为了确定短期暴露于环境臭氧是否与美国的死亡率有关.
- 调查每日和每周暴露于臭氧对死亡率的影响.
主要方法:
- 利用了来自美国95个大型城市社区 (1987-2000年) 国家发病率,死亡率和空气污染研究的数据.
- 采用分布式滞后和层次模型来估计全国平均死亡率,调整以考虑颗粒物和天气等混因素.
- 分析了总非伤害,心血管和呼吸道死亡率的每日计数.
主要成果:
- 每周暴露于臭氧的10ppb增加与每日死亡率上升0.52%.
- 随着每周臭氧增加,心血管和呼吸道死亡率增加了0.64%.
- 臭氧对死亡率的影响在更长的暴露时间 (每周或每天) 中更加明显,并在调整后保持强.
结论:
- 建立了短期臭氧波动与美国主要城市地区死亡率之间的统计学意义上的关联.
- 调查结果表明,环境臭氧是一个重要的公共卫生风险,影响了美国人口的很大一部分.
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