系统性炎症疾病中的眼睛.
Peter McCluskey1, Richard J Powell
1Department of Ophthalmology at St Vincent's Hospital and Royal Prince Alfred Hospital, Sydney, Australia. iritis@ozemail.com.au
Lancet (London, England)
|December 14, 2004
概括
系统性炎症性疾病会通过影响眼睛的各种结构来威胁视力. 区分眼部炎症与感染至关重要,特别是在免疫抑制患者中.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 系统性炎症性疾病经常影响眼睛结构,包括膜,角膜,视网膜和视轨.
- 这些情况对视力构成重大风险,包括血管性疾病和粒状炎症性疾病.
- 眼部并发症可能来自直接的炎症,缺血 (如动脉炎),高血压视网膜病变或药物的副作用,如黄素巨病变.
研究的目的:
- 突出系统性炎症疾病的多样化的眼部表现.
- 强调通过区分内源性眼内炎症和感染所带来的诊断挑战.
- 强调排除特定患者群体感染的重要性.
主要方法:
- 对临床表现和系统性炎症状况与眼部疾病之间的已知关联的审查.
- 分析视力丧失的潜在原因,包括直接炎症,缺血和药物毒性.
- 讨论诊断策略,特别是微生物研究在疑似感染病例中的作用.
主要成果:
- 系统性炎症可能导致直接的眼损伤和二次并发症,如缺血和药物诱导的黄斑病.
- 眼部感染,特别是在免疫抑制个体,可以模仿内源性眼内炎症.
- 在高风险患者中,必须考虑并通过适当的眼内液体和组织采样和培养排除感染.
结论:
- 在系统性炎症性疾病中眼部的参与需要全面的评估.
- 仔细区分炎症和感染对于适当的治疗和视力保护至关重要.
- 在疑似眼内炎症的免疫抑制患者中,诊断性体和微生物培养是必不可少的.
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