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Fbxw7/Cdc4是一种p53-依赖的,具有哈普洛因不足的瘤抑制基因

Jian-Hua Mao1, Jesus Perez-Losada, Di Wu

  • 1Cancer Research Institute, University of California at San Francisco, 2340 Sutter Street, San Francisco, California 94143, USA.

Nature
|December 14, 2004
PubMed
概括

Fbxw7基因充当瘤抑制剂,其损失有助于癌症的发展,特别是在p53缺乏的小鼠中. 这种平时的瘤抑制基因是不够的.

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