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CYP4A1120-hydroxyeicosatetraenoic acid合成酶的功能变体与基本高血压有关

James V Gainer1, Aouatef Bellamine, Elliott P Dawson

  • 1Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical School, Nashville, Tenn 37232-0146, USA.

Circulation
|December 22, 2004
PubMed
概括

在CYP4A11基因 (T8590C) 中的一种遗传变异减少了20-基酸 (20-HETE) 的产生. 这种变异与某些人群中高血压风险增加有关,突出其在血压调节中的作用.

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