通过药店直接获得紧急避孕措施,对意外怀孕和性传播疾病的影响:一项随机对照试验
Tina R Raine1, Cynthia C Harper, Corinne H Rocca
1Center for Reproductive Health Research and Policy, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA 94110, USA. rainet@obgyn.ucsf.edu
JAMA
|January 6, 2005
概括
通过药房直接获得紧急避孕药 (EC) 增加了其使用,但提前提供更有效. 公众健康的影响仍然有限,原因是使用率不足和高比例的无保护性交.
科学领域:
- 生殖健康 生殖健康
- 公共卫生 公共卫生
- 临床试验 临床试验
背景情况:
- 一半的意外怀孕可以通过更好的紧急避孕 (EC) 获取和使用来预防.
- 目前对EC的访问方法可能会对及时使用构成障碍.
研究的目的:
- 评估直接进入药房和提前提供EC对生殖健康结果的影响.
- 为了评估年轻女性的EC使用,怀孕率和性传播感染 (STIs).
主要方法:
- 一项随机对照试验,涉及2117名年龄在15-24岁的女性.
- 三组的比较:药房访问EC,提前提供EC (3包) 和标准诊所访问 (控制).
- 在6个月后测量的结果包括EC使用,怀孕,性传播感染,避孕药使用和性行为.
主要成果:
- 提前提供显著增加了EC使用率 (37.4%),相比对照 (21.0%),而药房准入没有 (24.2%).
- 两组之间没有观察到怀孕率或性传播感染率的显著差异.
- 避孕药和避孕套的使用,以及性行为,在所有研究部门保持一致.
结论:
- 虽然改善的接入增加了EC的吸收,但整体公共卫生影响受到利用不足和频繁的无保护性交的限制.
- 限制EC进入诊所并没有证据支持,因为药房准入和提前提供不会对避孕或性行为产生负面影响.
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