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Updated: May 2, 2026

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
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GSK-3β调节CRMP-2的酸化和神经元的极性

Takeshi Yoshimura1, Yoji Kawano, Nariko Arimura

  • 1Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan.

Cell
|January 18, 2005
PubMed
概括

糖原合成酶激酶-3β (GSK-3β) 通过酸化使缩蛋白反应介质蛋白-2 (CRMP-2) 失活,阻碍轴突的形成. 神经营养素-3 (NT-3) 禁用GSK-3β,通过激活CRMP-2来促进轴突生长.

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