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在阿尔茨海默氏症的β-粉样纤维细胞中,自我扩散的,分子水平的多态性

Aneta T Petkova1, Richard D Leapman, Zhihong Guo

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Bethesda, MD 20892-0520, USA.

Science (New York, N.Y.)
|January 18, 2005
PubMed
概括

不同的粉样β-40纤维结构,或形态学,与不同的毒性相关. 生长条件和播种影响这些自我传播的结构,影响阿尔茨海默病的机制和纳米材料的发展.

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Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds the telomeric...