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Updated: Aug 16, 2026

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
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通过单个氨酸残留物的可逆乙化调节的Stat3二元化

Zheng-Long Yuan1, Ying-Jie Guan, Devasis Chatterjee

  • 1Department of Surgery, Brown University Medical School-Rhode Island Hospital, Providence, RI 02903, USA.

Science (New York, N.Y.)
|January 18, 2005
PubMed
概括

信号传感器和转录3 (STAT3) 激活剂在Lys685上的乙化对于细胞因子诱导的基因转录和细胞生长至关重要. 这种修饰是通过基因素脱乙酶 (HDAC) 可逆的,对于STAT3二分化和DNA结合至关重要.

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