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通过向的抑制性受体表达恢复狼的耐受性

Tracy L McGaha1, Brian Sorrentino, Jeffrey V Ravetch

  • 1Laboratory of Molecular Genetics and Immunology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

Science (New York, N.Y.)
|February 1, 2005
PubMed
概括

在B细胞上恢复抑制性Fc受体 (FcγRIIB) 水平可以预防易患狼的小鼠自身免疫. 适度增加FcγRIIB表达足以恢复耐受性,并可能为自身免疫性疾病提供治疗.

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