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Larval RNA Interference in the Red Flour Beetle, Tribolium castaneum
Published on: October 13, 2014
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在甲甲虫Tribolium castaneum中,对膜状翅膀的同一性需要超比索拉克斯
Yoshinori Tomoyasu1, Scott R Wheeler, Robin E Denell
1Division of Biology, Chalmers Hall, Kansas State University, Manhattan, Kansas 66506, USA. tomoyasu@ksu.edu
Nature
|February 11, 2005
概括
在甲虫中,Ultrabithorax (Ubx) 基因将后翼修改为elytra,挑战了关于翅膀进化的先前想法. 这个霍克斯基因是霍克斯基因.
科学领域:
- 进化发育生物学 进化发育生物学
- 昆虫形态学 昆虫形态学
- 遗传学 是一个遗传学.
背景情况:
- 昆虫的翅膀进化涉及到祖先对的修改.
- 在果 (Drosophila melanogaster) 中,Hox基因Ultrabithorax (Ubx) 区分了前翼和后翼 (halteres).
- 在果中,UBX抑制了翅膀发育基因,促进了的身份.
研究的目的:
- 为了研究UBX在甲虫 (Tribolium castaneum) 翅膀修饰中的作用.
- 检查霍克斯基因输入是否对专门的翅膀衍生物或祖先翅膀至关重要.
- 了解昆虫翅膀多样化的进化机制.
主要方法:
- 在Tribolium castaneum甲虫中对Ubx的基因敲除.
- 翅膀形态和基因表达的比较分析.
- 研究石,伊洛quois,和achaete-scute同类的表达模式.
主要成果:
- 在甲虫中Ubx knockdown将后翼转化为elytra,这表明Ubx将后翼非专业化.
- 与预期相反,Elytra形成与没有Hox的状态有关.
- 后翼中的UBX活动会影响基因表达,将基因表达模式从以太子形状转变为翅膀形状.
结论:
- 乌布克斯在甲虫后翼中起到了抵消作用,促进了更为祖先的翅膀身份.
- 这代表了昆虫翅膀多样化的新机制.
- 霍克斯基因在翅膀进化中的功能比以前理解的更加复杂和多样.
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