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Updated: Jul 11, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
10:01

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

通过连接桥的多价值体预组织来进行蛋白质异构化:增强对两个蛋白质标的连接结

Jiyun Liu1, Zhongsheng Zhang, Xiaojian Tan

  • 1Biomolecular Structure Center, Department of Chemistry, University of Washington, Seattle, Washington 98195, USA.

Journal of the American Chemical Society
|February 17, 2005
PubMed
概括

研究人员设计了一种双功能连接体,将霍乱毒素B pentamer (CTB) 与人血清粉样蛋白P成分 (SAP) 联系起来. 这种蛋白质异构增强了对两个标的联结亲和力.

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