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Updated: Jul 14, 2026

Engineering 'Golden' Fluorescence by Selective Pressure Incorporation of Non-canonical Amino Acids and Protein Analysis by Mass Spectrometry and Fluorescence
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扩展氨酸的设计和合成,该氨酸对c-MYC G-四重复结构具有选择性

Jeyaprakashnarayanan Seenisamy1, Sridevi Bashyam, Vijay Gokhale

  • 1College of Pharmacy, The University of Arizona, 1703 East Mabel, Tucson, Arizona 85721, USA.

Journal of the American Chemical Society
|March 3, 2005
PubMed
概括

一种新型化合物Se2SAP选择性地结合并稳定了c-MYC G-四重复 DNA. 这种选择性结合提供了一个有前途的治疗策略,与现有化合物相比,光活性和细胞毒性降低.

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Tagging and Fusion Proteins01:24

Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...