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CD4+ T细胞帮助控制 CD8+ T细胞的记忆,通过 TRAIL介导的激活诱导的细胞死亡

Edith M Janssen1, Nathalie M Droin, Edward E Lemmens

  • 1Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.

Nature
|March 4, 2005
PubMed
概括

在启动过程中,CD4+ T细胞的帮助使CD8+ T细胞在再次遇到抗原时能够自主扩张,形成免疫记忆. 没有这种帮助,CD8+ T细胞会经历TRAIL介导的亡,突出了适应性免疫的新机制.

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