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Updated: May 11, 2026

Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs
11:00

Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs

Published on: June 12, 2018

微RNA参与AU丰富元素介导的mRNA不稳定性

Qing Jing1, Shuang Huang, Sabine Guth

  • 1Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|March 16, 2005
PubMed
概括

微RNA在信使RNA (mRNA) 中向富含AU元素 (AREs) 进行降解. 这一过程涉及Dicer和Argonaute蛋白质,对于调节ARE-mRNA稳定性至关重要.

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