白人,黑人和西班牙裔之间缺血性中风亚型发生率:北曼哈顿研究
Halina White1, Bernadette Boden-Albala, Cuiling Wang
1Department of Neurology, College of Physicians and Surgeons, USA.
Circulation
|March 17, 2005
概括
黑人和西班牙裔人比白人有更高的缺血性中风发病率,这是由于所有中风亚型的发病率增加. 这项在曼哈顿北部的基于人口的研究强调了中风风险的重大种族种族差异.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 与白人相比,黑人人群体中中风发病率明显高,西班牙裔人群的数据有限.
- 了解中风风险的种族种族差异需要检查亚型特定的缺血性中风发病率.
研究的目的:
- 确定和比较白色,黑色和西班牙裔人口中缺血性中风亚型的发病率,居住在一个社区.
- 阐明不同缺血性中风亚型对中风风险观察到的种族种族差异的贡献.
主要方法:
- 一项以人口为基础的研究,利用综合性中风监测系统,在曼哈顿北部的四年 (1993年7月 - 1997年6月) 期间识别第一个缺血性中风病例.
- 缺血性中风亚型使用修改后的国家神经疾病和中风研究所 (NINDS) 计划进行分类.
- 根据年龄调整的,特定于种族的发病率和中风亚型的相对率被计算出来,并在种族-民族群体之间进行了比较.
主要成果:
- 根据年龄调整,每10万人中第一次缺血性中风的年均发病率为白人88例,西班牙裔149例,黑人191例.
- 与白人相比,黑人患内动脉样硬化性中风 (5.85),外动脉样硬化性中风 (3.18),内中风 (3.09) 的相对比率显著更高.
- 与白人相比,西班牙裔的脑内动脉样性中风 (5.00) 和缺口性中风 (2.32) 的相对比率也较高.
结论:
- 与白人人口相比,在黑人和西班牙裔人口中观察到的缺血性中风的发病率增加是由于所有已识别的缺血性中风亚型中的更高率.
- 这些发现突显了中风风险的重大种族差异,受各种病因学亚型的影响.
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