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对Pb2+与GATA蛋白相互作用的光谱和功能性确定

Amy B Ghering1, Lisa M Miller Jenkins, Brandy L Schenck

  • 1Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.

Journal of the American Chemical Society
|March 18, 2005
PubMed
概括

(Pb2+) 与GATA蛋白密切结合,破坏它们的DNA结合和转录活动. 这表明GATA蛋白质是大脑和心脏中毒性的关键标.

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