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类型VII原是Ras驱动的人类表皮瘤发生所必需的

Susana Ortiz-Urda1, John Garcia, Cheryl L Green

  • 1VA Palo Alto Healthcare System, Palo Alto, CA 94304, USA.

Science (New York, N.Y.)
|March 19, 2005
PubMed
概括

七型原蛋白的缺陷会导致皮肤疾病并增加癌症风险. 一个特定的原VII片段 (NC1) 促进瘤生长和入侵,这表明瘤-肌瘤相互作用有助于癌症的发展,在衰退性缩性表皮溶解牛患者.

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