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Updated: Jul 7, 2026

In situ Subcellular Fractionation of Adherent and Non-adherent Mammalian Cells
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Published on: July 23, 2010

哺乳动物染色体聚集和分离所需的线粒体隔膜支架

Elias T Spiliotis1, Makoto Kinoshita, W James Nelson

  • 1Department of Molecular and Cellular Physiology, Beckman Center for Molecular and Genetic Medicine, Stanford University School of Medicine, Stanford, CA 94305-5435, USA.

Science (New York, N.Y.)
|March 19, 2005
PubMed
概括

七是一种蛋白质家族,在细胞分裂过程中形成了支架,以确保染色体正确分离,细胞运动完成. 七面体枯竭导致染色体损失和细胞分裂错误.

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.