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与哺乳动物相比,鱼的线粒体DNA进化的速度较慢
A P Martin1, G J Naylor, S R Palumbi
1Department of Zoology, University of Hawaii, Honolulu 96822.
Nature
|May 14, 1992
概括
分子时钟的速度在脊椎动物物种之间有很大差异. 鱼的线粒体DNA进化速度比灵长类动物慢7到8倍,因此需要对特定类别进行校准以获得准确的分子约会.
科学领域:
- 进化生物学 进化生物学
- 分子进化分子进化
- 基因组学就是基因组学.
背景情况:
- 线粒体DNA (mtDNA) 进化速率主要在灵长类动物中进行校准.
- 脊椎动物之间存在恒定的分子钟被广泛认为是假设,但未经测试.
- 以前的假设可能导致不准确的差异时间估计.
研究的目的:
- 在脊椎动物中测试分子时钟恒定假设.
- 为了检查鱼的线粒体DNA序列变异.
- 为了比较鱼和其他脊椎动物群体之间的进化速率.
主要方法:
- 分析了13种鱼物种的mtDNA序列变异.
- 测序的细胞色素b和细胞色素氧化酶I基因.
- 将替代率与灵长类和类动物数据进行比较,包括巴拿马半岛分隔的物种.
主要成果:
- 鱼mtDNA的替代率比灵长类或类动物慢7到8倍.
- 这种速率差异不能归因于核酸偏差,选择或基因选择.
- 在最近分离的鱼物种中确认了较慢的速度.
结论:
- 分子时钟在所有脊椎动物种群中并不恒定.
- 对其他群体使用以灵长类动物为基础的校准是不适当的.
- 对于高分辨率的分子进化研究来说,对特定类型的校准是必不可少的.
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