发展中国家的医院获得的新生儿感染
Anita K M Zaidi1, W Charles Huskins, Durrane Thaver
1Department of Paediatrics and Child Health, Aga Khan University, Stadium Road, PO Box 3500, Karachi 74800, Pakistan. ianita.zaidi@aku.edu
Lancet (London, England)
|March 30, 2005
概括
新生儿感染率在发展中国家明显高,原因是感染控制不良. 许多常见的病原体对标准治疗有抗性,这凸显了改善策略的迫切需要.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 新生儿护理 新生儿护理
背景情况:
- 发展中国家的医院出生的新生儿面临感染的风险较高.
- 低标准的产后和产后感染控制实践有助于增加这种风险.
研究的目的:
- 审查新生儿感染率,病原体,抗菌素耐药性和发展中国家的干预措施.
- 评估这些感染对新生儿结果和医疗保健系统的影响.
主要方法:
- 对发展中国家关于新生儿感染的数据进行系统审查.
- 分析病原体流行率,抗菌素敏感性和报告的感染控制干预措施.
主要成果:
- 新生儿感染率比工业化国家高3-20倍.
- 关键的病原体包括Klebsiella pneumoniae,克拉姆阴性杆菌 (大肠杆菌,黑人菌,青杆菌) 和金黄色葡萄球菌.
- 经验性抗生素方案,如安培素和 gentamicin 显示了有限的覆盖范围 (约. 70%的感染),许多病例在资源有限的环境中可能无法治疗.
结论:
- 新生儿感染率高和抗菌素耐药性对发展中国家的新生儿结果构成重大挑战.
- 使用质量改进方法的低成本,捆绑干预措施显示出希望,但需要特定背景的证据.
- 解决感染控制问题对于改善新生儿生存率和这些地区的长期健康至关重要.
相关概念视频
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