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Updated: Jul 19, 2026

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PDK1核化T细胞受体诱导的信号复合体,用于NF-kappaB激活

Ki-Young Lee1, Fulvio D'Acquisto, Matthew S Hayden

  • 1Section of Immunobiology and Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA.

Science (New York, N.Y.)
|April 2, 2005
PubMed
概括

3-氨基酸依赖性激酶1 (PDK1) 通过将T细胞受体 (TCR) 与NF-kappaB信号连接,对T细胞激活至关重要. PDK1调节蛋白激酶C (PKC) 和CARD11的招募,启动T细胞增殖和适应性免疫.

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