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Updated: Jul 11, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
05:46

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on: April 9, 2014

作为选择性抗HIV药物的脱氧三酸核化物

Tongfei Wu1, Matheus Froeyen, Veerle Kempeneers

  • 1Laboratories of Medicinal Chemistry and Virology, Rega Institute for Medical Research, Minderbroedersstraat 10, Leuven, Belgium.

Journal of the American Chemical Society
|April 7, 2005
PubMed
概括

两种新的酸核化物PMDTA和PMDTT显示出强大的抗HIV活性,没有观察到毒性. 它们通过HIV-1逆转录酶被纳入DNA,表明它们有可能作为抗病毒剂.

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