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Updated: Jul 20, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

在流体微芯片上进行单分子追踪,用于定量检测低丰度核酸

Tza-Huei Wang1, Yahui Peng, Chunyang Zhang

  • 1Department of Mechanical Engineering and Whitaker Biomedical Engineering Institute, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA. thwang@jhu.edu

Journal of the American Chemical Society
|April 14, 2005
PubMed
概括

这项研究引入了一种新的方法,可以使用先进的微流体学和光谱学准确检测稀缺的DNA/RNA分子. 该技术能够对低丰度核酸点进行敏感,快速和定量分析.

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...