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Updated: Jul 11, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
10:59

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

作为早期人类瘤形成中的候选抗癌障碍物的DNA损伤反应

Jirina Bartkova1, Zuzana Horejsí, Karen Koed

  • 1Institute of Cancer Biology and Centre for Genotoxic Stress Research, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark. jb@cancer.dk

Nature
|April 15, 2005
PubMed
概括

早期的癌细胞激活DNA损伤反应以防止瘤生长. 这种ATM-Chk2-p53通路的缺陷可能导致癌症进展和基因组不稳定.

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