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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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一种NMR方法用于确定蛋白质结合接口,使用二氧化物诱导的自旋格子放松增强剂

M Sakakura1, S Noba, P A Luchette

  • 1Contribution from the Graduate School of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|April 21, 2005
PubMed
概括

研究人员用氧气作为一个偏磁探头,用核磁共振 (NMR) 识别蛋白质结合接口. 这种方法通过分析放松率来有效检测结合部位,为其他技术提供了灵敏的替代方案.

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