这位患者是否患有骨髓质疏松症?
Katalin Scherer1, Richard S Bedlack, David L Simel
1Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. scher012@mc.duke.edu
JAMA
|April 21, 2005
概括
通过特定的历史细节和简单的测试,可以改善诊断肌痛性肌痛症 (MG). 偷看的标志,冰测试,EDROPHONIUM测试和睡眠测试有助于诊断MG.
科学领域:
- 神经学 神经学
- 临床诊断 临床诊断 临床诊断
- 医学研究 医学研究
背景情况:
- 准确及时诊断肌痛性肌痛症 (MG) 对于患者的护理至关重要.
- 诊断的延迟可能会导致这种可治疗的自身免疫性疾病的严重并发症.
研究的目的:
- 评估特定的历史因素和简单的诊断测试如何影响诊断肌痛严重症的概率.
- 确定改善MG诊断的关键临床指标.
主要方法:
- 对MEDLINE (1966-2005) 的英语文章和参考文献进行系统的文献综述.
- 包括评估症状,征兆和测试的诊断准确性的研究,包括患有和没有严重肌痛性肌痛症的患者.
- 数据提取和质量评估由两位独立审查员进行.
主要成果:
- "在长时间讲话时语音变得不明朗"的历史和视符号的存在显著增加了MG的可能性.
- 冰测试,测试和睡眠测试提供了有价值的诊断信息,异常结果增加,正常结果减少MG的概率.
- 其他评估的迹象和症状,如"吞后食物留在嘴里"和的眼睛运动,并没有显著改变诊断概率.
结论:
- 临床病史,体检结果 (例如,视标志) 和简单的床边测试 (冰,睡眠,) 对于诊断肌痛严重症非常有价值.
- 由于研究群体的潜在偏差,应谨慎解释结果.
- 需要进一步的研究来验证专家使用的常见诊断操作和历史特征.
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