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Updated: Jun 23, 2026

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
08:01

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Published on: May 30, 2012

卵巢外表达Oct-4阻断了原生细胞分化,并导致表皮组织的发育不良

Konrad Hochedlinger1, Yasuhiro Yamada, Caroline Beard

  • 1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

Cell
|May 11, 2005
PubMed
概括

一个关键的胚胎基因Oct-4在体组织中重新激活时,可以诱导成年小鼠的癌症生长. 这表明成年原生细胞可以恢复到类似胚胎的状态,推动瘤的形成.

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