戒烟,肺功能和体重增加:一个后续研究
Susan Chinn1, Deborah Jarvis, Roberto Melotti
1Department of Public Health Sciences, King's College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK. sue.chinn@kcl.ac.uk
Lancet (London, England)
|May 12, 2005
概括
戒烟可以改善肺功能,但体重增加会减少这些益处,尤其对男性来说. 控制体重对于最大限度地提高戒烟对呼吸系统健康的积极影响至关重要.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 关于戒烟和体重变化对肺功能的综合影响的国际数据有限.
- 以前的研究还没有完全阐明这些因素对呼吸道肺功能的净影响.
研究的目的:
- 估计戒烟对肺功能的净益.
- 确定吸烟和体重变化对呼吸道肺功能变化的独立影响.
主要方法:
- 利用了来自27个中心的6654名欧洲共同体呼吸系统健康调查参与者的数据.
- 在20-44岁的个体中,肺功能被测量了两次 (1991-93年和1998-2002年).
- 通过吸烟状态和体重变化分析了肺功能中的变化,调整为年龄和身高,并对性别进行了特定分析.
主要成果:
- 与从未吸烟者相比,戒烟与1秒内强迫呼气体积 (FEV1) 的下降率较低,特别是持续戒烟者.
- 吸烟者在FEV1.1下降的幅度更大.
- 体重增加显著降低了戒烟对FEV1的益处,男性的影响更为明显.
结论:
- 戒烟对肺功能有好处,这是保存FEV1.1所表明的.
- 有效的体重管理对于最大限度地提高戒烟带来的肺功能益处至关重要,特别是在男性中.
- 戒烟和体重变化之间的相互作用突出了维持呼吸系统健康的关键因素.
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