声心谱第三和第四心声与左心室功能的客观测量之间的关联
Gregory M Marcus1, Ivor L Gerber, Barry H McKeown
1Division of Cardiology, University of California, San Francisco, USA.
JAMA
|May 12, 2005
概括
第三个 (S3) 和第四个 (S4) 心声不是左心室功能障碍的敏感指标. 然而,S3心声显示出高特异性来检测这种情况,其性能优于S4.
科学领域:
- 心脏病学 心脏病学
- 医学诊断 医学诊断 医学诊断
- 生物医学工程 生物医学工程
背景情况:
- 第三个 (S3) 和第四个 (S4) 心声被认为是马声的标准标准.
- 他们对左心室功能障碍的诊断能力仍然未被探索.
研究的目的:
- 评估S3和S4心声在预测左心室功能障碍方面的诊断准确性.
- 使用计算机算法进行心声分析.
主要方法:
- 一项前性研究涉及90名接受心脏导管治疗的成年患者.
- 同时评估心脏声音 (S3/S4),左心室末端透气压 (LVEDP),左心室喷射率 (LVEF) 和B型尿素 (BNP).
- 使用已确定的左心室功能标志物的诊断测试特征的分析.
主要成果:
- 患有S3,S4或两者的患者表现出显著升高的LVEDP,降低的LVEF和更高的BNP水平.
- 对S3的敏感度为41% (LVEDP),52% (LVEF) 和32% (BNP);对于S4,它们为46% (LVEDP),43% (LVEF) 和40% (BNP).
- 对于S3的特异性是92% (LVEDP),87% (LVEF) 和92% (BNP);对于S4,它们是80% (LVEDP),72% (LVEF) 和78% (BNP).
结论:
- 声心谱S3和S4不是左心室功能障碍的敏感标记.
- 声心谱S3显示左心室功能障碍的高特异性,超过S4的中等特异性.
相关概念视频
Assessment of the Cardiovascular System IV: Auscultation
Cardiac auscultation is a clinical skill used to assess heart function and detect abnormalities. It involves listening to heart sounds at specific anatomical locations through a stethoscope.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
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Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
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