在碳纳米管模板上的功能性一维脂质双层
Alexander B Artyukhin1, Aleksei Shestakov, Jennifer Harper
1Biosecurity and Nanosciences Laboratory, Lawrence Livermore National Laboratory, California 94550, USA.
Journal of the American Chemical Society
|May 19, 2005
概括
研究人员在碳纳米管上创建了液体,自我愈合的1D脂质膜. 这些新的生物无机纳米结构显示出开发先进生物传感器和生物电子设备的前景.
科学领域:
- 生物有机的纳米结构
- 材料科学 材料科学 材料科学
- 生物物理学的生物物理.
背景情况:
- 生物机器和环境对于新的生物无机纳米结构至关重要.
- 模仿细胞膜的脂质双层对于生物传感器和生物NEMS设备至关重要.
研究的目的:
- 在碳纳米管模板上开发新的1D脂质膜.
- 研究这些生物灵感纳米结构的特性和潜在应用.
主要方法:
- 在聚合物缓冲碳纳米管周围支持的脂质双层的自发组装.
- 膜流动性和缺陷愈合能力的表征.
- 使用扩散模型建模脂质分子运动.
主要成果:
- 在碳纳米管模板周围成功形成连续的1D脂质纳米.
- 1-D脂质膜在多个损伤恢复周期中表现出流动性和自我愈合特性.
- 脂质分子的移动性被简单的扩散模型准确地描述.
结论:
- 开发出来的1D脂质膜代表了一类新的生物无机纳米结构.
- 这些流体和自我愈合的膜具有先进的生物传感器和生物电子设备的巨大潜力.
- 这些发现为纳米技术和生物技术的创新应用铺平了道路.
更多相关视频
09:20Fabrication of Low Temperature Carbon Nanotube Vertical Interconnects Compatible with Semiconductor Technology
Published on: December 7, 2015
09:12Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering
Published on: June 1, 2016
相关概念视频
Asymmetric Lipid Bilayer
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
Assembly of the Lipid Bilayer in the ER
Biological membranes are more than just a barrier separating cell cytoplasm from the outside environment. They are highly dynamic and help maintain the integrity and physiological stability of the cells as well as membrane-bound organelles. Membranes also play vital roles in cell-to-cell and intracellular communication.
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
