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Smad1保护心肌细胞免受缺血-再输液损伤的影响

Mitsuru Masaki1, Masahiro Izumi, Yuichi Oshima

  • 1Department of Molecular Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita City, Osaka 565-0871, Japan.

Circulation
|May 25, 2005
PubMed
概括

Smad1信号通路通过减少心肌细胞亡来保护成人心脏免受缺血-再输液 (I/R) 损伤. 在小鼠中过度表达Smad1,在I/R事件后显著减少心脏损伤和细胞死亡.

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