结核病和无家可归在美国,1994-2003年
Maryam B Haddad1, Todd W Wilson, Kashef Ijaz
1Surveillance, Epidemiology, and Outbreak Investigations Branch, Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Ga 30333, USA. maryam.haddad@cdc.hhs.gov
JAMA
|June 9, 2005
概括
无家可归与结核病 (TB) 有关. 尽管面临挑战,但结核病无家可归者可以通过良好的病例管理实现优异的治疗结果,并显示结核病例的年均比例稳定.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 美国无家可归人口中的结核病 (TB) 率由于被排除在美国人口普查数据之外,因此无法精确计算.
- 无家可归常常与结核病的风险增加有关.
研究的目的:
- 为了描述那些患有结核病的无家可归者.
- 为了比较无家可归者和非无家可归者之间的结核病风险因素和疾病特征.
主要方法:
- 通过从国家结核病监测系统 (1994-2003) 中验证的结核病例进行了横截面分析.
- 数据包括人口特征,风险因素,疾病表现,治疗和无家可归和非无家可归结核病患者的结果.
主要成果:
- 在1994年至2003年期间,185,870例结核病例中有6.1%-6.7%与无家可归有关.
- 患有结核病的无家可归者更有可能是男性,年长,有物质使用障碍和艾滋病毒同时感染.
- 无家可归者的结核病更具传染性,但不具有更强的抗药性;结果与非无家可归的个人相似,特别是直接观察治疗.
结论:
- 结核病风险因素经常与无家可归的风险因素重叠,突出了结核病管理中的社会背景的重要性.
- 有效的病例管理和直接观察治疗对于无家可归人群中结核病治疗的成功结果至关重要.
相关概念视频
Biological Effects of Radiation
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
NF-κB-dependent Signaling Pathway
The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
Restorative Care
Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
Classification of Illness
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...


