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Updated: May 9, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
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激活循环自酸化是由DYRKs的一种新型过渡中间形式介导的

Pamela A Lochhead1, Gary Sibbet, Nick Morrice

  • 1The Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow G61 1BD, Scotland, United Kingdom. p.lochhead@beatson.gla.ac.uk

Cell
|June 18, 2005
PubMed
概括

蛋白激酶通过自酸化成熟,这是以前无法解释的过程. 这项研究表明,双特异性氨酸酸化调节蛋白激酶 (DYRKs) 通过一种在翻译过程中涉及暂时中间体的分子内机制来实现这一目标.

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