肥胖是否是冠状动脉旁路手术中死亡的风险因素?
Ruyun Jin1, Gary L Grunkemeier, Anthony P Furnary
1Providence Health System, Portland, Ore, USA. Ruyun.Jin@providence.org
Circulation
|June 22, 2005
概括
身体质量指数 (BMI) 并不是冠状动脉旁路移植 (CABG) 手术后死亡的重要风险因素. 然而,高正常至超重的BMI患者的死亡率最低.
科学领域:
- 心血管外科心血管外科
- 肥胖问题研究研究
- 临床风险评估临床风险评估
背景情况:
- 关于身体质量指数 (BMI) 对冠状动脉绕道移植 (CABG) 手术后死亡率的影响存在相互矛盾的证据.
- 之前的研究已经给出了不一致的结果,即肥胖是否是CABG患者住院死亡的重要风险因素.
研究的目的:
- 为了研究体质指数 (BMI) 和冠状动脉旁路移植 (CABG) 患者的住院死亡率之间的关系.
- 澄清包括肥胖在内的不同BMI类别在预测CABG手术结果中的作用.
主要方法:
- 分析了一大群包括16218名在1997年至2003年期间接受单独CABG的患者.
- 利用后勤回归和分数多项式转换来评估BMI对住院死亡率的影响.
- 采用累积总和技术来确定各种BMI组的死亡率趋势.
主要成果:
- 在各种评估方法中,身体质量指数 (BMI) 没有被发现是医院内死亡率的统计学上显著预测指标.
- 累计总和分析显示,高正常和超重的BMI类别的患者表现出最低的风险调整后死亡率.
- 在BMI值低于高正常范围或高于超重类别的患者中观察到轻微增加的死亡率.
结论:
- 按BMI测量的整体体积并不是CABG手术后死亡的重要风险因素.
- 在高正常和超重的BMI子组中观察到最低的住院死亡率.
- 与最佳BMI范围相比,体重不足和肥胖患者的死亡率趋势略高.
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