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Obesity01:24

Obesity

1.6K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

349
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
349
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

404
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
404
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

1.7K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

440
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
440
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

597
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Updated: Apr 13, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
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Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice

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肥胖是否是冠状动脉旁路手术中死亡的风险因素?

Ruyun Jin1, Gary L Grunkemeier, Anthony P Furnary

  • 1Providence Health System, Portland, Ore, USA. Ruyun.Jin@providence.org

Circulation
|June 22, 2005
PubMed
概括

身体质量指数 (BMI) 并不是冠状动脉旁路移植 (CABG) 手术后死亡的重要风险因素. 然而,高正常至超重的BMI患者的死亡率最低.

科学领域:

  • 心血管外科心血管外科
  • 肥胖问题研究研究
  • 临床风险评估临床风险评估

背景情况:

  • 关于身体质量指数 (BMI) 对冠状动脉绕道移植 (CABG) 手术后死亡率的影响存在相互矛盾的证据.
  • 之前的研究已经给出了不一致的结果,即肥胖是否是CABG患者住院死亡的重要风险因素.

研究的目的:

  • 为了研究体质指数 (BMI) 和冠状动脉旁路移植 (CABG) 患者的住院死亡率之间的关系.
  • 澄清包括肥胖在内的不同BMI类别在预测CABG手术结果中的作用.

主要方法:

  • 分析了一大群包括16218名在1997年至2003年期间接受单独CABG的患者.
  • 利用后勤回归和分数多项式转换来评估BMI对住院死亡率的影响.
  • 采用累积总和技术来确定各种BMI组的死亡率趋势.

主要成果:

  • 在各种评估方法中,身体质量指数 (BMI) 没有被发现是医院内死亡率的统计学上显著预测指标.
  • 累计总和分析显示,高正常和超重的BMI类别的患者表现出最低的风险调整后死亡率.
  • 在BMI值低于高正常范围或高于超重类别的患者中观察到轻微增加的死亡率.

结论:

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  • 按BMI测量的整体体积并不是CABG手术后死亡的重要风险因素.
  • 在高正常和超重的BMI子组中观察到最低的住院死亡率.
  • 与最佳BMI范围相比,体重不足和肥胖患者的死亡率趋势略高.