制造均的磁性纳米复合材料球体,具有磁性核心/半孔甲外结构
Wenru Zhao1, Jinlou Gu, Lingxia Zhang
1State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Science, Shanghai 200050, People's Republic of China.
Journal of the American Chemical Society
|June 23, 2005
概括
新型磁芯/半孔甲纳米圈被合成用于向药物输送和多相分离. 从二氧化外释放的布洛芬表明了该材料在受控释放应用中的潜力.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
- 化学 化学 化学
背景情况:
- 开发先进的纳米材料对于药物输送和分离技术的应用至关重要.
- 半孔性二氧化纳米粒子为各种应用提供高表面积和可调节的孔状结构.
- 磁性纳米粒子提供远程操纵能力,用于有针对性的输送和分离.
研究的目的:
- 为了合成新的磁核/半孔贝纳米球.
- 描述合成纳米球的磁性和结构性质.
- 为了证明在向药物输送和多相分离中的潜在应用.
主要方法:
- 合成磁芯/半孔甲外纳米球,直径约为270nm.
- 粒子大小,表面积和孔径体积的表征.
- 证明ibuprofen的储存和释放从半孔的贝.
主要成果:
- 成功合成了统一的磁芯/半孔甲外纳米球.
- 纳米球具有磁性特性,这是由于外的核心和高表面积/孔积.
- 证明控制的存储和释放布洛芬,展示了药物输送的潜力.
结论:
- 合成的磁芯/半孔甲纳米球对向药物输送具有前景.
- 该材料的性能适用于多相分离应用.
- 进一步的研究可以探索不同的药物加载和释放配置文件.
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