传染性内心炎的时间趋势:明尼苏达州奥尔姆斯特德县的一项基于人口的研究
Imad M Tleyjeh1, James M Steckelberg, Hani S Murad
1Department of Medicine, Division of Infectious Diseases, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minn, USA. tleyjeh.imad@mayo.edu
JAMA
|June 24, 2005
概括
在奥尔姆斯特德县,传染性内心炎 (IE) 的发病率在过去三十年中保持稳定. 维里丹群链球菌是IE最常见的原因,比金黄色葡萄球菌更为常见.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 有限的基于人口的数据存在于传染性内心炎 (IE) 发病率的流行病学变化.
- 了解时间趋势对于公共卫生战略和资源分配至关重要.
研究的目的:
- 评估感染性内心炎 (IE) 发生率的时间趋势.
- 为了评估IE临床特征随时间变化的变化.
主要方法:
- 一项基于人口的调查,利用罗切斯特流行病学项目在明尼苏达州奥姆斯特德县进行.
- 从1970年到2000年,在102名住院居民中分析了107次IE发作,使用修改的杜克标准进行了诊断.
主要成果:
- 经年龄和性别调整的IE发病率在研究期间没有显著变化,在每10万人/年中从5.0到7.0例不等.
- 维里达群链球菌仍然是最常见的致病生物体,其次是金黄色葡萄球菌,对任何一种都没有发现显著的时间趋势.
- 在患有潜在心脏病的患者中,假肢IE和心交脱落的趋势呈上升趋势,而风湿性心脏病的趋势呈下降趋势.
结论:
- 这项以社区为基础的研究发现,在30年内,IE发病率没有实质性的变化.
- 在这个群体中,维里丹斯群链球菌总是数量超过金黄色葡萄球菌作为IE的主要致病原体.
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