信息传单和针对急性下呼吸道感染的抗生素处方策略:一个随机对照试验
Paul Little1, Kate Rumsby, Joanne Kelly
1Primary Medical Care Group, University of Southampton, Highfield, England. p.little@soton.ac.uk
JAMA
|June 24, 2005
概括
对于急性下呼吸道感染,延迟或不提供抗生素是有效的,并减少了抗生素的使用. 这种方法对患者来说是可以接受的,并且不会显著延长症状持续时间.
科学领域:
- 初级医疗保健医学 一级医疗保健医学
- 传染性疾病 传染性疾病
- 临床试验 临床试验
背景情况:
- 急性下呼吸道感染是一种常见的初级保健诊断.
- 对这些感染的抗生素处方很常见,但对有效性的证据是混合的.
研究的目的:
- 评估三种抗生素处方策略和急性下呼吸道感染信息传单的有效性.
- 为了比较即时抗生素,延迟抗生素和没有抗生素,有或没有信息传单.
主要方法:
- 一项随机对照试验,涉及807名患有急性无并发性下呼吸道感染的患者.
- 患者被分配到接受立即,延迟或没有抗生素的组,有或没有信息传单.
主要成果:
- 在抗生素处方策略之间,没有发现症状持续时间或严重程度的显著差异.
- 延迟或不采取抗生素策略显著减少了抗生素使用和患者对抗生素有效性的信念.
- 信息传单对主要结果没有影响,但与更高的复诊率有关.
结论:
- 暂停或延迟抗生素治疗急性下呼吸道感染是一种可行的策略.
- 这种方法可以减少抗生素消耗和对抗生素的依赖,而不会影响症状的解决.
- 患者的接受度和满意度在各个策略中都是可比的,在非处方组中,抗生素期望降低.
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