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相关概念视频

Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

6.0K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
6.0K
Hormonal Regulation01:40

Hormonal Regulation

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
47.7K
Overview of Secretory Vesicles01:33

Overview of Secretory Vesicles

9.3K
Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
9.3K
Insulin Secretory Vesicles01:05

Insulin Secretory Vesicles

6.3K
Insulin secretory vesicles release insulin to stimulate blood glucose uptake and regulate carbohydrate metabolism. When the blood glucose levels increase, glucose enters the pancreatic β-islet cells through glucose transporters. Once inside, glucose is metabolized through glycolysis, the citric acid cycle, and the electron transport chain, producing ATP. This increase in ATP concentration closes ATP-sensitive potassium channels, leading to depolarization of the membrane and the opening of...
6.3K
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

2.1K
The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...
2.1K
Feedback Inhibition00:46

Feedback Inhibition

56.8K
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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相关实验视频

Updated: Jan 10, 2026

Regulation of Hormone Secretion
01:19

Regulation of Hormone Secretion

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通过微生物纳米线进行细胞外电子转移.

Gemma Reguera1, Kevin D McCarthy, Teena Mehta

  • 1Department of Microbiology, University of Massachusetts, Amherst, Massachusetts 01003, USA.

Nature
|June 24, 2005
PubMed
概括

硫缩菌 (Geobacter sulfurreducens pili) 作为生物纳米线,将电子转移到Fe (III) 氧化物中,用于微生物呼吸. 这一发现揭示了细胞外电子转移的新机制,以及生物工程导电材料的潜力.

科学领域:

  • 微生物学 微生物学
  • 地质化学 地质化学
  • 生物物理学的生物物理.

背景情况:

  • 细胞外电子转移对于微生物有机物降解和营养循环至关重要.
  • 外膜c型细胞染色体一直是微生物Fe降低的主要焦点.
  • 一些减少Fe的微生物,如Geobacter物种,缺乏c-cytochromes,需要替代的电子转移机制.

研究的目的:

  • 研究 pili 在 Geobacter sulfurreducens 的细胞外电子转移到 Fe ((iii) 氧化物中的作用.
  • 为了确定 pili 是否对于 Fe (III) 氧化物减少在 Geobacter 物种中至关重要.
  • 为了探索Geobacter sulfurreducens pili. 的导电性质.

主要方法:

  • 构建和分析Geobacter sulfurreducens.的一个缺少pilus的突变菌.
  • 在野生型和突变菌株中评估Fe (III) 氧化物减少能力.
  • 使用导探探头原子力显微镜来评估 pili 的导电性.

主要成果:

  • 缺的Geobacter sulfurreducens突变体失去了减少Fe (III) 氧化物的能力.
  • 突变菌株保留了与Fe (III) 氧化物结合的能力,这表明 pili 不仅仅用于粘附.

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相关实验视频

Last Updated: Jan 10, 2026

Regulation of Hormone Secretion
01:19

Regulation of Hormone Secretion

6.0K
Hormonal Regulation of Digestion
01:40

Hormonal Regulation of Digestion

47.7K
Overview of Secretory Vesicles
01:33

Overview of Secretory Vesicles

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  • 导体探针原子力显微镜表明,这些具有高度导电性.

    • 结论:

    • 硫缩菌 (Geobacter sulfurreducens pili) 作为生物纳米线,促进电子从细胞转移到细胞外Fe (III) 氧化物.
    • 皮利介导的电子转移代表了微生物呼吸和生物地球化学循环的新机制.
    • 皮利的导电性为生物工程新型导电生物材料和理解独特的细胞表面相互作用开辟了道路.