双三甲) 介导的二乙烯合成:用N,N-二基-4-乙烯氨酸与醇的氧化化
Terunobu Saitoh1, Junji Ichikawa
1Department of Chemistry, Graduate School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Journal of the American Chemical Society
|July 7, 2005
概括
一种新的方法可以在不加热的情况下高效地合成基亚氨基乙烯. 这种氧化 arylation 使用一种新型的 dication 催化剂进行基因基替代,提供了一个更绿色的合成路径.
科学领域:
- 有机化学 有机化学
- 合成化学 合成化学
背景情况:
- 乙烯是药品和材料科学中重要的结构动图.
- 替代性乙烯的高效合成仍然是有机化学的一个关键挑战.
研究的目的:
- 开发一种新,高效和温和的方法来合成各种阿里4-二甲基亚胺乙烯.
- 通过使用特定的滴定催化剂来探索氧化和的机制.
主要方法:
- 类与N,N-二甲基-4-甲基亚尼林的反应.
- 通过 bis ((diphenylmethylium) naphthalenediyl 分解进行催化.
- 激进的过程,涉及到乙基组的ipso-substitution.
主要成果:
- 在良好的产量中合成了各种阿里尔4-二甲基亚胺乙烯.
- 反应有效地进行,不需要加热.
- 催化系统证明了有效地促进了氧化 arylation.
结论:
- 已经建立了一种新且高效的乙烯合成方法.
- 双 (二甲) 纳二二酸是这种转化的一个有效催化剂.
- 反应通过一个涉及ipso-substitution的激进机制进行.
相关概念视频
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