妇女的循环雄激素水平和自我报告的性功能
Susan R Davis1, Sonia L Davison, Susan Donath
1Women's Health Program, Department of Medicine, Monash Medical School, Alfred Hospital, Victoria, Australia. susan.davis@med.monash.edu.au <susan.davis@med.monash.edu.au>
JAMA
|July 7, 2005
概括
这项研究发现,低丸激素和女性性功能障碍之间没有直接联系. 虽然在特定的年龄组中观察到一些与脱二二酸盐的关联,但没有单一的雄激素水平预测性功能低下.
科学领域:
- 内分泌学 在内分泌学.
- 性健康 性的健康
- 妇女健康 妇女健康
背景情况:
- 低丸激素和女性性功能障碍之间的建议联系缺乏强有力的证据.
- 调查血清雄激素水平与女性自我报告的性功能之间的关系.
研究的目的:
- 为了确定性欲/性满意度低的女性是否有较低的血清雄激素水平.
- 检查特定的性功能领域和雄激素水平之间的关联.
主要方法:
- 在澳大利亚维多利亚州,对1021名年龄在18-75岁的女性进行了横截面研究.
- 使用女性性功能概况 (PFSF) 评估性功能.
- 测量了总体/自由的血清水平,安德罗二和脱水二硫酸盐 (DHEA-S).
主要成果:
- 没有发现低性功能和低总/自由或androstenedione之间的显著关联.
- 45岁以上女性的低性反应与较低的DHEA-S水平有关 (OR,3.90).
- 18-44岁女性的低性欲,兴奋和反应能力与较低的DHEA-S水平 (ORs从3.86到6.59) 有关.
结论:
- 没有单一的雄激素水平可靠地预测女性性功能障碍.
- 大多数低DHEA-S水平的女性不会经历性功能低下.
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