代谢综合征和黑人心声图左心室质量:社区动脉样硬化风险研究 (ARIC)
Cecil M Burchfiel1, Thomas N Skelton, Michael E Andrew
1Jackson Heart Study, National Heart, Lung, and Blood Institute, Jackson, Mississippi, USA. cburchfiel@cdc.gov
Circulation
|August 3, 2005
概括
代谢综合征与黑人成年人左心室 (LV) 质量增加有关. 这种关联主要是由LV壁厚度驱动的,而不是腔室大小,突出了心血管风险.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 代谢综合征与心血管疾病有关.
- 关于代谢综合征与左心室 (LV) 质量等亚临床措施的联系存在有限的研究.
- 这种关系在黑人群体中至关重要,其中代谢综合征和LV缩是普遍存在的.
研究的目的:
- 为了研究代谢综合征和心声回声图左心室 (LV) 质量之间的关系.
- 为了检查这个协会,特别是在一个黑人人口,考虑到这两个条件的高患病率.
主要方法:
- 心声学评估了来自社区动脉样硬化风险研究 (ARIC) 的1572名黑人成年人 (49-75岁) 的LV尺寸.
- 参与者根据代谢综合征特征的数量进行分组:高血压,脂质不良和葡萄糖不耐受.
- 经过对生活方式因素和中心脂肪度进行调整后的统计分析.
主要成果:
- 根据身高指数的LV质量显著逐步增加,并观察到更多的代谢综合征特征.
- LV 后壁和腹腔间隔膜厚度,但不是 LV 腔的大小,与代谢综合征集群显著相关.
- 高血压显示出强烈的影响,失脂症和葡萄糖不耐受性有助于,但没有发现显著的协同效应.
结论:
- 在黑人男性和女性中,代谢综合征聚类与增加的LV质量和壁壁厚度密切相关.
- 这些发现表明,胰岛素抵抗等潜在因素可能会影响心肌缩,而不是心室扩张.
- 这项研究强调了代谢健康和该人群中亚临床心脏结构变化之间的关键联系.
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