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开发一种准动态的药模型,用于抗补剂类型的抗补剂类型

Buddhadeb Mallik1, Dimitrios Morikis

  • 1Department of Chemical and Environmental Engineering, University of California at Riverside, Riverside, CA 92521, USA.

Journal of the American Chemical Society
|August 4, 2005
PubMed
概括

用于补充抑制的compstatin的药理学模型是使用分子动力学来开发的. 二维模型有效地区分了活性与非活性类似物,突出了药物设计中的的灵活性.

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