在冷却末端切除中,导管尖端和组织温度之间的差异:对于指导左心房切除的相关性
G Keith Bruce1, T Jared Bunch, Mark A Milton
1Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Circulation
|August 10, 2005
概括
导管尖端温度不准确地反映了冷却尖端切除过程中的组织温度. 微泡形成可能表明过热,这表明需要减少射频能量.
科学领域:
- 心血管干预 心血管干预
- 电力生理学 电力生理学
- 生物医学工程 生物医学工程
背景情况:
- 冷却尖端切除术用于心律失常.
- 在切除过程中精确估计组织温度对于安全性和有效性至关重要.
- 导管尖温度,组织温度,功率和微泡形成之间的关系尚未得到充分理解.
研究的目的:
- 为了研究冷却尖端切除过程中导管尖端和组织温度之间的差异.
- 探索功率,温度和微泡形成之间的相关性.
- 为了确定微泡形成是否可以可靠地预测组织过热.
主要方法:
- 在九只狗身上使用冷却尖端导管进行了射频能量传递.
- 监测了导管尖和组织温度.
- 功率被定位以观察微泡的形成,以心内心声谱为指导.
- 在剥离过程中记录了阻抗变化.
主要成果:
- 导管尖端温度平稳,而组织温度随着功率的增加而显著增加.
- 在重叠的温度和功率范围内形成的I型和II型微气泡.
- 微泡形成,特别是I型,发生在比II型更低的功率和温度下.
- 没有微泡或存在I型微泡并不排除过度组织加热.
结论:
- 在冷却尖端切除过程中,导管尖和组织之间存在显著的温度差异.
- 微泡形成是潜在组织过热的指标,可以减少能量输送.
- 目前的监测方法可能无法完全捕捉在切除过程中过度组织加热的风险.
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