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谷氨素5的缺乏表明Fe-S集群是脊椎动物血合成所需的

Rebecca A Wingert1, Jenna L Galloway, Bruce Barut

  • 1Stem Cell Program and Division Hematology/Oncology Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|August 20, 2005
PubMed
概括

铁硫 (Fe-S) 集群组装对于血红蛋白生产至关重要. 这项研究表明,斑马鱼中受损的Fe-S集群组装激活铁调节蛋白1 (IRP1),阻断血生物合成.

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