Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
Preparation of Diols and Pinacol Rearrangement01:57

Preparation of Diols and Pinacol Rearrangement

Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
Carboxylic Acid Derivatives: Overview01:15

Carboxylic Acid Derivatives: Overview

Carboxylic acid derivatives are formed by replacing the hydroxyl group of carboxylic acids with a different functional group. The most common carboxylic acid derivatives are:
Acid Halides to Esters: Alcoholysis01:12

Acid Halides to Esters: Alcoholysis

Alcoholysis is a nucleophilic acyl substitution reaction in which an alcohol functions as a nucleophile. Acid halides react with alcohol to produce esters. The mechanism proceeds in three steps:
Peptidoglycan Synthesis01:28

Peptidoglycan Synthesis

Structure of PeptidoglycanPeptidoglycan is a vital structural component of the bacterial cell wall, providing mechanical strength and shape to the cell. It consists of repeating units of two sugars—N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM)—linked by β-1,4 glycosidic bonds. These sugar chains are cross-linked by short peptide chains, forming a mesh-like polymer that surrounds the bacterial plasma membrane.Cytoplasmic Phase – Precursor SynthesisPeptidoglycan biosynthesis begins in...
Formation of Lipopolysaccharides01:19

Formation of Lipopolysaccharides

Lipopolysaccharides (LPS) are crucial components of the outer membrane of Gram-negative bacteria, serving both structural and functional roles. It contributes to membrane stability and protects bacteria from host immune responses. LPS is composed of three major regions—lipid A, a core oligosaccharide, and an O antigen. The biosynthesis and assembly of LPS involve a highly coordinated set of enzymatic reactions and transport mechanisms. Additionally, LPS is recognized as an endotoxin, triggering...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Effects of Serum Incubation on Lipid Nanoparticle PEG Shedding, mRNA Retention, and Membrane Interactions.

ACS applied materials & interfaces·2025
Same author

Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by <sup>1</sup>H NMR and All-Atom Molecular Dynamics Simulations.

Molecular pharmaceutics·2022
Same author

Evolution of Complexity. Molecular Aspects of Preassembly.

Molecules (Basel, Switzerland)·2021
Same author

An Alternative Molecular View of Evolution: How DNA was Altered over Geological Time.

Molecules (Basel, Switzerland)·2020
Same author

Coordination among Bond Formation/Cleavage in a Bifunctional-Catalyzed Fast Amide Hydrolysis: Evidence for an Optimized Intramolecular <i>N</i>-Protonation Event.

The Journal of organic chemistry·2020
Same author

Interaction vs Preorganization in Enzyme Catalysis. A Dispute That Calls for Resolution.

ACS chemical biology·2019

相关实验视频

Updated: Jul 19, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

描述由两性皮科林酸盐形成的"外阶段".

Fredric M Menger1, Ashley L Galloway, Dan Lundberg

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA. menger@emory.edu

Journal of the American Chemical Society
|August 25, 2005
PubMed
概括

一些皮科林酸盐在水滴周围形成稳定,自我修复的外,当在水/烯混合物中超声波. 这些外,很可能是固体或半固体薄膜,是由分子自我组装驱动的,溶解性阻碍了它们的形成.

科学领域:

  • 超分子化学 超分子化学
  • 材料科学 材料科学 材料科学
  • 物理化学 物理化学

背景情况:

  • 皮科林酸盐是有机化合物,具有多样化的应用.
  • 了解自组装机制对于开发新型材料至关重要.
  • 微结构的受控形成是纳米技术的一个关键挑战.

研究的目的:

  • 为了研究皮科林酸盐的外结构的形成和特性.
  • 阐明能量输入和溶剂混合物在形成中的作用.
  • 探索控制皮科林酸盐自组装的结构-活性关系.

主要方法:

  • 在水/托卢混合物中对皮科林酸盐溶液进行超声波和旋转.
  • 显微镜和物理操作 (例如,针刺) 来描述的特性.
  • 对十种不同的皮科林酸盐化合物进行结构-活性关系分析.

主要成果:

  • 稳定,大约600A厚的外围绕水滴形成.
  • 弹在受到物理损伤后表现出自我修复的能力.
  • 在水或二烯阶段的溶解性抑制了贝的形成.
  • 没有结晶性表明固体或半固体薄膜结构.

更多相关视频

Isolation and Compositional Analysis of Plant Cuticle Lipid Polyester Monomers
09:47

Isolation and Compositional Analysis of Plant Cuticle Lipid Polyester Monomers

Published on: November 22, 2015

Chemical Isolation, Quantification, and Separation of Skin Lipids from Reptiles
07:55

Chemical Isolation, Quantification, and Separation of Skin Lipids from Reptiles

Published on: February 7, 2019

相关实验视频

Last Updated: Jul 19, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Isolation and Compositional Analysis of Plant Cuticle Lipid Polyester Monomers
09:47

Isolation and Compositional Analysis of Plant Cuticle Lipid Polyester Monomers

Published on: November 22, 2015

Chemical Isolation, Quantification, and Separation of Skin Lipids from Reptiles
07:55

Chemical Isolation, Quantification, and Separation of Skin Lipids from Reptiles

Published on: February 7, 2019

  • 链链结合和结合被确定为主导的自我组装力量.

    • 结论:

    • 皮科林酸盐可以通过能量驱动的自组装在水滴表面上形成坚固的,自我愈合的微型外.
    • 芳香溶剂和特定的分子相互作用 (链链结合,结合) 对于的形成至关重要.
    • 这些发现为设计具有可调节性质的功能性超分子材料提供了洞察力.