疟疾风险:估计疟疾的临床发作
Bernard L Nahlen1, Eline L Korenromp, John M Miller
1World Health Organization, Roll Back Malaria Department, 1211 Geneva, Switzerland.
Nature
|September 9, 2005
概括
疟疾疾病负担估计对于控制计划至关重要. 最近的研究表明,全球的Plasmodium falciparum病例比以前报告的要高,特别是在非洲以外.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 准确的疟疾疾病负担估计对于有效的公共卫生干预至关重要.
- 在全球疟疾病例估计中存在差异,特别是在Plasmodium falciparum方面.
- 以前对疟疾负担的比较依赖于过时的世界卫生组织 (WHO) 数据.
研究的目的:
- 将斯诺及其同事的疟疾病例估计与世界卫生组织 (WHO) 数据进行比较.
- 澄清疟疾负担报告中的差异,特别是在非洲以外的地区.
- 突出对疟疾全球影响的不断发展的理解.
主要方法:
- 对疟疾病例估计的比较分析.
- 审查不同组织发布的疟疾负担数据.
- 关注的是Plasmodium falciparum疟疾病例.
主要成果:
- 斯诺及其同事估计,全球有5.15亿个Plasmodium falciparum病例,高于一些世卫组织数据.
- 斯诺及其同事引用的比较使用过时的世卫组织估计 (1990,1998) 而不是当前范围 (2000年以后).
- 斯诺的小组和世卫组织都同意,非洲以外的疟疾负担,特别是在南亚,比以前认为的要高.
结论:
- 疟疾疾病负担估计需要仔细考虑所使用的数据来源和时间框架.
- 对于非洲以外的疟疾负担日益增加存在共识.
- 全球疟疾控制工作需要更新和一致的估计方法.
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