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Updated: Jul 15, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

PUMA 结合了p53的核和细胞质前的功能

Jerry E Chipuk1, Lisa Bouchier-Hayes, Tomomi Kuwana

  • 1Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, CA 92121, USA.

Science (New York, N.Y.)
|September 10, 2005
PubMed
概括

瘤抑制剂Trp53 (p53) 在亡中具有不同的核和细胞质作用. 一个Bcl-xL,p53和PUMA的相互作用协调这些功能,PUMA对于启动亡至关重要.

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